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A polymer microarray of 120 polyurethanes was used to identify polymers that promoted the adhesion of bone marrow dendritic cells (BMDC). Identified polymers were coated onto glass cover slips and shown to be efficient substrates for the immobilisation of these primary cells, which underwent efficient phagocytosis while still presumably maintaining their immature state.

Original publication

DOI

10.1016/j.biomaterials.2006.04.040

Type

Journal article

Journal

Biomaterials

Publication Date

10/2006

Volume

27

Pages

5299 - 5306

Addresses

School of Medicine, University of Southampton, Mail Point 824, Southampton General Hospital, Southampton, Hants SO16 6YD, UK.

Keywords

Dendritic Cells, Bone Marrow Cells, Cells, Immobilized, Animals, Mice, Inbred C57BL, Mice, Polyurethanes, Biological Assay, Cell Adhesion, Phagocytosis, Female, Male