The human HLA-A(*)0201 allele, expressed in hamster cells, is not a high-affinity receptor for adenovirus type 5 fiber
Davison E., Kirby I., Elliott T., Santis G.
The coxsackie B virus and adenovirus receptor (CAR) and the major histocompatibility complex (MHC) class I α2 domain have been identified as high-affinity cell receptors for adenovirus type 5 (Ad5) fiber. In this study we show that CAR but not MHC class I allele HLA-A(*)0201 binds to Ad5 with high affinity when expressed on hamster cells. When both receptors are coexpressed on the cell surface of hamster cells, Ad5 fiber bind to a single high-affinity receptor, which is CAR.