Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain

Brand M., Clayton J., Moroglu M., Schiedel M., Picaud S., Bluck JP., Skwarska A., Bolland H., Chan AKN., Laurin CMC., Scorah AR., See L., Rooney TPC., Andrews KH., Fedorov O., Perell G., Kalra P., Vinh KB., Cortopassi WA., Heitel P., Christensen KE., Cooper RI., Paton RS., Pomerantz WCK., Biggin PC., Hammond EM., Filippakopoulos P., Conway SJ.

DOI

10.1021/acs.jmedchem.1c00348

Type

Journal article

Journal

Journal of Medicinal Chemistry

Publisher

American Chemical Society (ACS)

Publication Date

13/07/2021

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