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BackgroundChildren with cancer are not at increased risk of severe SARS-CoV-2 infection; however, adults with haematological malignancies have increased risk of severe infections compared with non-haematological malignancies.MethodsWe compared patients with haematological and non-haematological malignancies enrolled in the UK Paediatric Coronavirus Cancer Monitoring Project between 12 March 2020 and 16 February 2021. Children who received stem cell transplantation were excluded.ResultsOnly 2/62 patients with haematological malignancy had severe/critical infections, with an OR of 0.5 for patients with haematological compared with non-haematological malignancies.InterpretationChildren with haematological malignancies are at no greater risk of severe SARS-CoV-2 infection than those with non-haematological malignancies.

Original publication




Journal article


Archives of disease in childhood

Publication Date





186 - 188


Cancer Research UK Clinical Trials Unit, University of Birmingham Institute of Cancer and Genomic Sciences, Birmingham, UK


Humans, Hematologic Neoplasms, Severity of Illness Index, Risk Assessment, Risk Factors, Cohort Studies, Adolescent, Child, Child, Preschool, Infant, Female, Male, COVID-19, SARS-CoV-2