Fine-tuning activity-dependent bulk endocytosis via kinases and phosphatases.

Milosevic I., Cousin MA.

The regulation of activity-dependent bulk endocytosis, the dominant mode of membrane retrieval in response to intense neuronal activity, is poorly understood. In this JCB issue, Peng et al. (2021. J. Cell. Biol.https://doi.org/10.1083/jcb.202011028) propose a novel molecular mechanism for the coordination of activity-dependent bulk endocytosis that builds on Minibrain kinase and its presynaptic substrate synaptojanin-1.

DOI

10.1083/jcb.202111056

Type

Journal article

Journal

The Journal of cell biology

Publication Date

12/2021

Volume

220

Addresses

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, National Institute for Health Research Oxford Biomedical Research Centre, Oxford, UK.

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