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A patient with a nasal neuroblastoma was found to have hypertension and severe hyponatraemia. Radiotherapy and cytotoxic chemotherapy were ineffective in reducing the size and vascularity of the neoplasm. Assay of tumor tissue post mortem revealed high levels of arginine vasopressin. The possibility of vasopressin formation to be added to the better known potential hormonal secretory activities of neuroblastomas.

Original publication

DOI

10.1002/1097-0142(19800301)45:5<961::aid-cncr2820450521>3.0.co;2-v

Type

Journal article

Journal

Cancer

Publication Date

03/1980

Volume

45

Pages

961 - 966

Keywords

Humans, Neuroblastoma, Nose Neoplasms, Hypertension, Hyponatremia, Adolescent, Female, Arginine Vasopressin