Comparison of Whole-Genome Sequence-Based Methods and PCR Ribotyping for Subtyping of Clostridioides difficile
Baktash A., Corver J., Harmanus C., Smits WK., Fawley W., Wilcox MH., Kumar N., Eyre DW., Indra A., Mellmann A., Kuijper EJ.
Clostridioides difficile is the most common cause of antibiotic-associated gastrointestinal infections. Capillary electrophoresis (CE)-PCR ribotyping is currently the gold standard for C. difficile typing but lacks the discriminatory power to study transmission and outbreaks in detail.