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Summary Bispecific T-cell engagers and chimeric antigen receptor T cells share the problem of eliciting acute systemic inflammation episodes known as cytokine release syndrome. Knowledge on the sequential waves of cytokines that can be neutralized with clinically available agents is crucial to prevent or treat this condition without jeopardizing the antitumor therapeutic outcome. See related article by Leclercq-Cohen et al., p. 4449

Original publication

DOI

10.1158/1078-0432.ccr-23-1975

Type

Journal article

Journal

Clinical Cancer Research

Publisher

American Association for Cancer Research (AACR)

Publication Date

01/11/2023

Volume

29

Pages

4320 - 4322