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Paired nasopharyngeal and oropharyngeal swabs collected from 533 children hospitalized with lower respiratory tract infection were assessed by multiplex reverse transcription-PCR. Oropharyngeal swabs increased the number of viral infections detected by 15%, compared to collection of a nasopharyngeal swab alone. This advantage was most pronounced for detection of influenza, parainfluenza, and adenovirus.

Original publication

DOI

10.1128/JCM.02605-10

Type

Journal article

Journal

J Clin Microbiol

Publication Date

06/2011

Volume

49

Pages

2318 - 2320

Keywords

Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Nasopharynx, Oropharynx, Respiratory Tract Infections, Reverse Transcriptase Polymerase Chain Reaction, Sensitivity and Specificity, Specimen Handling, Virology, Virus Diseases, Viruses