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PAC1 receptor–mediated clearance of tau in postsynaptic compartments attenuates tau pathology in mouse brain

Schaler AW., Runyan AM., Clelland CL., Sydney EJ., Fowler SL., Figueroa HY., Shioda S., Santa-Maria I., Duff KE., Myeku N.

PAC1 receptor activation enhances proteasome-mediated clearance of tau from postsynaptic compartments in the tau transgenic mouse brain.

Original publication

DOI

10.1126/scitranslmed.aba7394

Type

Journal article

Journal

Science Translational Medicine

Publisher

American Association for the Advancement of Science (AAAS)

Publication Date

26/05/2021

Volume

13