Presence of a multidrug-resistance mutation in an HIV-2 variant infecting a treatment-naive individual in Caio, Guinea Bissau.
Jallow S., Vincent T., Leligdowicz A., De Silva T., Van Tienen C., Alabi A., Sarge-Njie R., Aaby P., Corrah T., Whittle H., Jaye A., Vanham G., Rowland-Jones S., Janssens W.
We report the possible transmission of drug-resistant human immunodeficiency virus type 2. A 66-year-old woman from rural Guinea Bissau who had no obvious antiretroviral exposure was found to harbor a variant with the multidrug-resistance mutation Q151M. Finding this mutation among a drug-naive population presents an important public health issue that needs to be addressed for treatment to be effective.