Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The relation between maternal anti-D concentrations, measured against the British working standard, and outcome of rhesus-sensitised pregnancies was studied. There is a clear relation between increasing anti-D concentrations and the chance of a severely affected baby. Of those pregnancies (78) where serial anti-D concentrations remained below 4 IU/ml, no baby had a cord haemoglobin below 10 g/dl and three had exchange transfusions. In contrast, of those mothers (106) with anti-D concentrations above 4 IU/ml, 23 had babies with a cord haemoglobin below 10 g/dl and 79 babies had exchange transfusions. It is suggested that those pregnancies where anti-D concentrations remain below 4 IU/ml represent a relatively safe group in which amniocentesis may be avoided.

Original publication

DOI

10.1136/bmj.285.6338.327

Type

Journal article

Journal

Br Med J (Clin Res Ed)

Publication Date

31/07/1982

Volume

285

Pages

327 - 329

Keywords

Bilirubin, Erythroblastosis, Fetal, Exchange Transfusion, Whole Blood, Female, Fetal Blood, Hemoglobins, Humans, Infant, Newborn, Isoantibodies, Pregnancy, Prognosis, Rh-Hr Blood-Group System, Rho(D) Immune Globulin