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Summary The presence of moieties denoting viral infection is crucial to mount powerful cytotoxic T-cell immune responses acting through innate receptors such as Toll-like receptor 3. For cancer immunotherapy, several safe analogues of viral double-stranded RNA are under clinical development following compelling evidence for efficacy in mouse models. See related article by van Eijck et al., p. 3447

Original publication

DOI

10.1158/1078-0432.ccr-24-0938

Type

Journal article

Journal

Clinical Cancer Research

Publisher

American Association for Cancer Research (AACR)

Publication Date

15/08/2024

Volume

30

Pages

3355 - 3357