Malaria endemicity linked to shorter telomeres in leukocytes.

Band G., Leffler EM.

Leukocyte telomere length is a highly polygenic trait that has been associated with a complex range of lifestyle factors and disease risk. McQuillan et al.'s results comparing telomere length to malaria incidence rates suggest that infections may be another important factor, possibly through permanent shortening of telomeres in hematopoietic progenitor cells.

DOI

10.1016/j.pt.2024.06.017

Type

Journal article

Journal

Trends in parasitology

Publication Date

08/2024

Volume

40

Pages

660 - 661

Addresses

Centre for Human Genetics, University of Oxford, Oxford, UK.

Keywords

Leukocytes, Telomere, Humans, Malaria, Incidence, Endemic Diseases, Telomere Shortening

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