Figure 4 from Dynamic Tracking of Tumor Microenvironment Modulation Using Kaede Photoconvertible Transgenic Mice Unveils New Biological Properties of Viral Immunotherapy

<p>No significant changes of CD8⁺ T cell in the dLN following CAN-2409 treatment. <b>A,</b> Quantification of total CD8⁺ T cell in the tumor dLN. <b>B,</b> Representative flow cytometry plots for KG⁺ and KR⁺ populations of CD8⁺ T cells and quantification are shown in <b>C</b> for KR⁺ CD8⁺ T cells. <b>D,</b> Quantification of Ki67⁺ percentage in the KG⁺CD8⁺T cells. <b>E,</b> Quantification of total TAA–specific (CD44^hi MC38 pentamer⁺) CD8⁺ T cell in the tumor dLN. <b>F,</b> Quantification of Ki67⁺ percentage in TAA–specific KG⁺CD8⁺T cells. <b>G,</b> KR⁺ percent of TAA–specific (MC38 pentamer⁺) CD8⁺ T cell. All data are measured by flow cytometry. <i>N</i> = 4–6 mice per group. Two-tailed <i>t</i> test, **, <i>P</i> < 0.01.</p>