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Studies and trials in the field are key to the development of a vaccine for malaria. Our limited knowledge of naturally acquired immunity and of transmission dynamics and disease causation in the field imposes limitations on our ability to predict the efficacy of candidate vaccinations, and the eventual outcome on deploying an efficacious vaccine at a population level.

Original publication

DOI

10.1002/eji.200939529

Type

Journal article

Journal

Eur J Immunol

Publication Date

08/2009

Volume

39

Pages

2007 - 2010

Keywords

Animals, Antigens, Protozoan, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Humans, Immunity, Life Cycle Stages, Malaria Vaccines, Malaria, Falciparum, Models, Immunological, Plasmodium falciparum