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Levels of different acute phase proteins were compared in sera from parasitaemic and non-parasitaemic women living in a Plasmodium falciparum endemic area of Thailand. The ability of their sera to interfere with hepatic stage development of the parasite was examined. Correlations were found between levels of alpha-1 antitrypsin, alpha-2 macroglobulin, hemopexin and the potential of sera to block hepatocyte invasion by the sporozoite.

Original publication

DOI

10.1051/parasite/1995023263

Type

Journal article

Journal

Parasite

Publication Date

09/1995

Volume

2

Pages

263 - 268

Keywords

Acute-Phase Proteins, Adolescent, Adult, Animals, Antibodies, Protozoan, Cells, Cultured, Female, Humans, Immunity, Innate, Liver, Malaria, Mice, Mice, Inbred BALB C, Plasmodium falciparum, Plasmodium yoelii, Thailand