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A picture is emerging of how HIV subverts a normal immunological surveillance mechanism to establish primary infection. This involves the infection of dendritic cells at mucosal surfaces: as these cells then mature, they transport the virus to lymphoid tissue, where viral replication begins and infection of CD4(+) T cells occurs.


Journal article


Curr Biol

Publication Date





R248 - R250


Dendritic Cells, HIV, HIV Infections, Humans