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The aim of this study was to determine the efficacy of a killed Salmonella vaccine and three live vaccines in preventing caecal colonisation of Hy-line Brown pullets by Salmonella Enteritidis PT 4. The lowest number of Salmonella-positive birds following the largest challenge (10(8) cfu) was recorded for live vaccine 1. However, birds treated with the killed vaccine had a significantly lower number of salmonellae in their caeca compared with both the control group and the other vaccine groups (P<0.05).


Journal article


Vet Rec

Publication Date





493 - 496


Animals, Cecum, Chickens, Colony Count, Microbial, Drug Administration Schedule, Euthanasia, Animal, Female, Poultry Diseases, Salmonella Infections, Animal, Salmonella Vaccines, Salmonella enteritidis, United Kingdom, Vaccines, Attenuated, Vaccines, Inactivated