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The influence of haptoglobin polymorphisms on severe malaria occurrence was assessed in 1183 individuals from The Gambia. No significant association was found between severe malaria and either haptoglobin genotypes or phenotypes. The advantages of using a deoxyribonucleic acid-based haptoglobin typing method are discussed.

Type

Journal article

Journal

Trans R Soc Trop Med Hyg

Publication Date

05/2002

Volume

96

Pages

327 - 328

Keywords

Case-Control Studies, Gambia, Gene Frequency, Genetic Predisposition to Disease, Genotype, Haptoglobins, Humans, Immunity, Innate, Malaria, Falciparum, Polymorphism, Genetic