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Crystals of recombinant platelet-derived endothelial cell growth factor (PD-ECGF) were obtained by the hanging drop vapour diffusion technique. The crystals belong to the space group P2(1)2(1)2(1) with unit cell dimensions a = 63.7 A, b = 70.4 A, c = 219.6, alpha = beta = gamma = 90 degrees, and probably contain a single dimer in the asymmetric unit. Diffraction to a minimum Bragg spacing of 3.5 A has been obtained using a synchrotron X-ray source.

Original publication

DOI

10.1006/jmbi.1993.1632

Type

Journal article

Journal

J Mol Biol

Publication Date

05/12/1993

Volume

234

Pages

879 - 880

Keywords

Blood Platelets, Crystallization, Crystallography, X-Ray, Endothelial Growth Factors, Humans, Protein Conformation, Recombinant Proteins