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Simple 1-substituted 5- and 6-isoxazolyl-benzimidazoles have been shown to be potent inhibitors of the BET bromodomains with selectivity over the related bromodomain of CBP.

Original publication

DOI

10.1039/c2md20189e

Type

Journal article

Journal

MedChemComm

Publisher

Royal Society of Chemistry (RSC)

Publication Date

2013

Volume

4

Pages

140 - 144