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Etest susceptibilities to amoxicillin, chloramphenicol, and trimethoprim-sulfamethoxazole of 240 invasive isolates of Haemophilus influenzae cultured from children in rural Kenya were 66%, 66%, and 38%, respectively. Resistance increased markedly over 9 years and was concentrated among serotype b isolates. In Africa, the increasing cost of treating resistant infections supports economic arguments for prevention through conjugate H. influenzae type b immunization.

Original publication

DOI

10.1128/AAC.49.7.3021-3024.2005

Type

Journal article

Journal

Antimicrob Agents Chemother

Publication Date

07/2005

Volume

49

Pages

3021 - 3024

Keywords

Anti-Bacterial Agents, Child, Child, Preschool, Drug Resistance, Bacterial, Female, Haemophilus Infections, Haemophilus influenzae, Haemophilus influenzae type b, Hospitalization, Humans, Infant, Kenya, Male, Meningitis, Haemophilus, Microbial Sensitivity Tests, Pneumonia, Bacterial