Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

There are no contemporary data available describing human immunity to novel influenza A/H7N9. Using 1723 prospectively collected serum samples in southern Vietnam, we tested for antibodies to 5 avian influenza virus antigens, using a protein microarray. General-population antibody titers against subtype H7 virus are higher than antibody titers against subtype H5 and lower than titers against H9. The highest titers were observed for human influenza virus subtypes. Titers to avian influenza virus antigens increased with age and with geometric mean antibody titer to human influenza virus antigens. There were no titer differences between the urban and the rural location in our study.

Original publication

DOI

10.1093/infdis/jit224

Type

Journal article

Journal

J Infect Dis

Publication Date

15/08/2013

Volume

208

Pages

554 - 558

Keywords

H7N9, influenza, microarray, pandemic, serology, Antibodies, Viral, Humans, Influenza A virus, Influenza, Human, Prospective Studies, Protein Array Analysis, Seroepidemiologic Studies, Vietnam