DOCK8 is critical for the survival and function of NKT cells
Crawford G., Enders A., Gileadi U., Stankovic S., Zhang Q., Lambe T., Crockford TL., Lockstone HE., Freeman A., Arkwright PD., Smart JM., Ma CS., Tangye SG., Goodnow CC., Cerundolo V., Godfrey DI., Su HC., Randall KL., Cornall RJ.
Key PointsThe development and survival of mature NKT cells are impaired in DOCK8-deficient mice. DOCK8 is required for antigen-induced NKT cell proliferation and cytokine production.