The three-dimensional structure of foot-and-mouth disease virus at 2.9 A resolution.
Acharya R., Fry E., Stuart D., Fox G., Rowlands D., Brown F.
The structure of foot-and-mouth disease virus has been determined at close to atomic resolution by X-ray diffraction without experimental phase information. The virus shows similarities with other picornaviruses but also several unique features. The canyon or pit found in other picornaviruses is absent; this has important implications for cell attachment. The most immunogenic portion of the capsid, which acts as a potent peptide vaccine, forms a disordered protrusion on the virus surface.