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UNLABELLED: SelSim is a program for Monte Carlo simulation of DNA polymorphism data for a recombining region within which a single bi-allelic site has experienced natural selection. SelSim allows simulation from either a fully stochastic model of, or deterministic approximations to, natural selection within a coalescent framework. A number of different mutation models are available for simulating surrounding neutral variation. The package enables a detailed exploration of the effects of different models and strengths of selection on patterns of diversity. This provides a tool for the statistical analysis of both empirical data and methods designed to detect natural selection. AVAILABILITY: SUPPLEMENTARY INFORMATION:

Original publication




Journal article



Publication Date





3673 - 3675


Animals, Biological Evolution, Computer Simulation, Genetic Variation, Genetics, Population, Humans, Models, Genetic, Models, Statistical, Recombination, Genetic, Selection, Genetic, Software