Glycophorin C (CD236R) mediates vivax malaria parasite rosetting to normocytes
Lee W-C., Malleret B., Lau Y-L., Mauduit M., Fong M-Y., Cho JS., Suwanarusk R., Zhang R., Albrecht L., Costa FTM., Preiser P., McGready R., Renia L., Nosten F., Russell B.
Key PointsP vivax infected cells rosette exclusively to normocytes. Thus, rosetting does not directly facilitate P vivax merozoite invasion. Glycophorin C (CD236R) mediates vivax malaria parasite rosetting. This finding will help in the search for the P vivax rosette ligand.