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The dihydropteroate synthase (dhps) genes of 44 P. malariae strains from four Asian countries were isolated. Only a limited number of polymorphisms were observed. Comparison with homologous mutations in other Plasmodium species showed that these polymorphisms are unlikely to be associated with sulfadoxine resistance.

Original publication

DOI

10.1371/journal.pone.0093942

Type

Journal article

Journal

PLoS One

Publication Date

2014

Volume

9

Keywords

Antimalarials, Bangladesh, DNA, Protozoan, Dihydropteroate Synthase, Drug Resistance, Laos, Plasmodium malariae, Polymorphism, Genetic, Sulfadoxine, Thailand, Vietnam