Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries.
Tanomsing N., Mayxay M., Newton PN., Nosten F., Dolecek C., Hien TT., White NJ., Day NPJ., Dondorp AM., Imwong M.
The dihydropteroate synthase (dhps) genes of 44 P. malariae strains from four Asian countries were isolated. Only a limited number of polymorphisms were observed. Comparison with homologous mutations in other Plasmodium species showed that these polymorphisms are unlikely to be associated with sulfadoxine resistance.