Human CD68 promoter GFP transgenic mice allow analysis of monocyte to macrophage differentiation in vivo
Iqbal AJ., McNeill E., Kapellos TS., Regan-Komito D., Norman S., Burd S., Smart N., Machemer DEW., Stylianou E., McShane H., Channon KM., Chawla A., Greaves DR.
Key Points CD68-GFP reporter mice show GFP transgene expression in both monocytes and tissue resident macrophage populations. Adoptively transferred CD68-GFP monocytes maintain GFP expression after recruitment in an ongoing inflammatory response.