The crystal structure of the RhoA–AKAP-Lbc DH–PH domain complex
Abdul Azeez KR., Knapp S., Fernandes JMP., Klussmann E., Elkins JM.
The crystal structure of the RhoGEF domain of AKAP-Lbc in complex with RhoA combined with nucleotide exchange assays explain differences to related RhoGEF proteins and allow the possibility of targeting the AKAP-Lbc RhoGEF domain with small molecules.