Please mind the gap: axonal transport deficits in multiple sclerosis neurodegeneration.
Dendrou CA., Fugger L.
In this issue, Sorbara et al. (2014) demonstrate that axonal transport impairment is an early feature of neurodegeneration in multiple sclerosis models. This transport deficit is reversible by anti-inflammatory intervention but, if untreated, can contribute to late-stage axonal dystrophy.