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<jats:title>ABSTRACT</jats:title><jats:p>This study investigated the comparative accuracy of a recombinant 56-kDa type-specific antigen-based rapid diagnostic test (RDT) for scrub typhus for the detection of IgM antibodies by using conventional serology in well-characterized serum samples from undifferentiated febrile illness patients. The RDT showed high specificity and promising comparative accuracy, with 82% sensitivity and 98% specificity for samples defined positive at an IgM indirect immunofluorescence assay positivity cutoff titer of ≥1:1,600 versus 92% and 95% at ≥1:6,400, respectively.</jats:p>

Original publication

DOI

10.1128/cvi.00390-15

Type

Journal article

Journal

Clinical and Vaccine Immunology

Publisher

American Society for Microbiology

Publication Date

10/2015

Volume

22

Pages

1130 - 1132