The Human Vaccines Project: A roadmap for cancer vaccine development
Romero P., Banchereau J., Bhardwaj N., Cockett M., Disis ML., Dranoff G., Gilboa E., Hammond SA., Hershberg R., Korman AJ., Kvistborg P., Melief C., Mellman I., Palucka AK., Redchenko I., Robins H., Sallusto F., Schenkelberg T., Schoenberger S., Sosman J., Türeci Ö., Van den Eynde B., Koff W., Coukos G.
<jats:p>Cancer vaccine development has been vigorously pursued for 40 years. Immunity to tumor antigens can be elicited by most vaccines tested, but their clinical efficacy remains modest. We argue that a concerted international effort is necessary to understand the human antitumor immune response and achieve clinically effective cancer vaccines.</jats:p>