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OBJECTIVE: To identify the features of concurrent hepatitis C virus (HCV) infection in liver biopsies from patients thought to have alcoholic liver disease. PATIENTS: Fifty-five patients with a history of excess alcohol consumption were studied. METHODS: All patients underwent liver biopsy. RESULTS: Eight of the 55 patients studied were found to be HCV-positive. CONCLUSION: The histological features found to be most useful for identifying concurrent HCV infection were the presence of lymphoid aggregates in portal tracts (predictive value 100%), the presence of lymphocytes in the lobules (predictive value 83%), and the pattern of fibrosis, particularly periportal spurring rather than perivenular fibrosis (predictive value 75%).

Type

Journal article

Journal

Eur J Gastroenterol Hepatol

Publication Date

04/1995

Volume

7

Pages

331 - 334

Keywords

Adult, Aged, Biopsy, Chronic Disease, Female, Hepatitis C, Humans, Liver, Liver Diseases, Alcoholic, Male, Middle Aged