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The susceptibility of common marmosets and cotton-top tamarins to infection by HIV-2 in vivo was tested. One year and 19 months, respectively, post-inoculation, sera taken from three of four animals from each species are reactive for HIV-2 antibodies and HIV-specific nucleotide sequences were demonstrated in short-term cultures of PBL from two cotton-top tamarins. The animals remain in good health.

Type

Journal article

Journal

Journal of medical primatology

Publication Date

01/1989

Volume

18

Pages

329 - 335

Addresses

Institute of Cancer Research, Chester Beatty Laboratories, London, England.

Keywords

Animals, Cebidae, Aotus trivirgatus, Callitrichinae, Callithrix, Saguinus, HIV-1, HIV-2, Acquired Immunodeficiency Syndrome, Disease Models, Animal, DNA, Viral, HIV Antibodies, Blotting, Western, Enzyme-Linked Immunosorbent Assay, Blotting, Southern, Nucleic Acid Hybridization