Measuring the Plasmodium falciparum HRP2 protein in blood from artesunate-treated malaria patients predicts post-artesunate delayed hemolysis
Ndour PA., Larréché S., Mouri O., Argy N., Gay F., Roussel C., Jauréguiberry S., Perillaud C., Langui D., Biligui S., Chartrel N., Mérens A., Kendjo E., Ghose A., Hassan MMU., Hossain MA., Kingston HWF., Plewes K., Dondorp AM., Danis M., Houzé S., Bonnefoy S., Thellier M., Woodrow CJ., Buffet PA.
Previously parasitized erythrocytes in patients with severe malaria retain the parasite protein HRP2, which can be used to predict hemolysis induced by the drug artesunate.