Abnormal diurnal variation in salt and water excretion in patients with obstructive sleep apnoea
Warley ARH., Stradling JR.
<jats:p>1. In healthy individuals, sleep is associated with a fall in urine and sodium output.</jats:p> <jats:p>2. Seven male patients with obstructive sleep apnoea exhibited a paradoxical rise in both urine and sodium output during the hours of sleep.</jats:p> <jats:p>3. Continuous positive airway pressure applied via the nose abolished both the apnoea and the nocturnal rise in urine and sodium output, thereby restoring the diurnal pattern towards normal.</jats:p>