Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

From a prospective cohort study on tuberculosis/human immunodeficiency virus (TB/HIV) interaction in Addis Ababa, Ethiopia, drug susceptibility results were available for 94 TB patients (46% HIV-infected). Resistance to one or more drug(s) was detected in 21 (22.3%) and multidrug resistance in five (5.3%) patients. Occurrence of resistance was not related to HIV status or outcome after 24 months of follow-up. However, among HIV-infected TB patients who died during follow-up, survival time in those with a resistant Mycobacterium tuberculosis strain was significantly shorter compared to those with a sensitive strain (6 vs. 13 months). Early detection of drug resistance and timely treatment change can therefore have a positive impact on survival in HIV-infected TB patients.

Type

Journal article

Journal

Int J Tuberc Lung Dis

Publication Date

11/2004

Volume

8

Pages

1388 - 1391

Keywords

Adult, Antitubercular Agents, Case-Control Studies, Drug Resistance, Bacterial, Ethiopia, Female, Follow-Up Studies, HIV Infections, Humans, Male, Mycobacterium tuberculosis, Prospective Studies, Time Factors, Treatment Outcome, Tuberculosis, Pulmonary, Young Adult