A Controlled Trial of Mass Drug Administration to Interrupt Transmission of Multidrug-Resistant Falciparum Malaria in Cambodian Villages
Tripura R., Peto TJ., Chea N., Chan D., Mukaka M., Sirithiranont P., Dhorda M., Promnarate C., Imwong M., von Seidlein L., Duanguppama J., Patumrat K., Huy R., Grobusch MP., Day NPJ., White NJ., Dondorp AM.
In Cambodian villages, 3-month mass drug administration with high coverage using dihydroartemisinin-piperaquine was safe and was followed by the absence of clinical Plasmodium falciparum cases for at least 1 year, despite the presence of multidrug-resistant parasites.