Whole-Genome Sequencing for Predicting Clarithromycin Resistance in Mycobacterium abscessus
Lipworth S., Hough N., Leach L., Morgan M., Jeffery K., Andersson M., Robinson E., Smith EG., Crook D., Peto T., Walker T.
Mycobacterium abscessus is emerging as an important pathogen in chronic lung diseases, with concern regarding patient-to-patient transmission. The recent introduction of routine whole-genome sequencing (WGS) as a replacement for existing reference techniques in England provides an opportunity to characterize the genetic determinants of resistance.