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To evaluate risk factors for human infection with influenza A subtype H5N1, we performed a matched case-control study in Vietnam. We enrolled 28 case-patients who had laboratory-confirmed H5N1 infection during 2004 and 106 age-, sex-, and location-matched control-respondents. Data were analyzed by matched-pair analysis and multivariate conditional logistic regression. Factors that were independently associated with H5N1 infection were preparing sick or dead poultry for consumption < or =7 days before illness onset (matched odds ratio [OR] 8.99, 95% confidence interval [CI] 0.98-81.99, p = 0.05), having sick or dead poultry in the household < or =7 days before illness onset (matched OR 4.94, 95% CI 1.21-20.20, p = 0.03), and lack of an indoor water source (matched OR 6.46, 95% CI 1.20-34.81, p = 0.03). Factors not significantly associated with infection were raising healthy poultry, preparing healthy poultry for consumption, and exposure to persons with an acute respiratory illness.

Original publication

DOI

10.3201/eid1212.060829

Type

Journal article

Journal

Emerg Infect Dis

Publication Date

12/2006

Volume

12

Pages

1841 - 1847

Keywords

Adolescent, Adult, Animals, Case-Control Studies, Child, Child, Preschool, Female, Humans, Infant, Influenza A Virus, H5N1 Subtype, Influenza, Human, Logistic Models, Male, Poultry, Poultry Diseases, Risk Factors, Surveys and Questionnaires, Vietnam, Zoonoses