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Background to the debate: Current guidelines recommend that all fever episodes in African children be treated presumptively with antimalarial drugs. But declining malarial transmission in parts of sub-Saharan Africa, declining proportions of fevers due to malaria, and the availability of rapid diagnostic tests mean it may be time for this policy to change. This debate examines whether enough evidence exists to support abandoning presumptive treatment and whether African health systems have the capacity to support a shift toward laboratory-confirmed rather than presumptive diagnosis and treatment of malaria in children under five. © 2009 English et al.

Original publication

DOI

10.1371/journal.pmed.1000015

Type

Journal article

Journal

PLoS Medicine

Publication Date

01/01/2009

Volume

6

Pages

0007 - 0009