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Search results (59)

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A lower X-gate in TASK channels traps inhibitors within the vestibule

Rödström KEJ. et al, (2020), Nature, 582, 443 - 447

Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2.

Wang Q. et al, (2020), Structure (London, England : 1993), 28, 169 - 184.e5

Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation.

Yu X. et al, (2019), eLife, 8

The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K

Bushell SR. et al, (2019), Nature Communications, 10

A pharmacological master key mechanism that unlocks the selectivity filter gate in K + channels

Schewe M. et al, (2019), Science, 363, 875 - 880

A Pharmacological Masterkey Mechanism to Unlock the Selectivity Filter Gate in K plus Channels

Schewe M. et al, (2019), BIOPHYSICAL JOURNAL, 116, 301A - 302A

Understanding Protein-Lipid Interactions of TRP Channels of the Polycystin Family, through MD Simulations and Structural Studies

Wang Q. et al, (2019), BIOPHYSICAL JOURNAL, 116, 534A - 535A

The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K

Bushell SR. et al, (2018)

ZMPSTE24 missense mutations that cause progeroid diseases decrease prelamin A cleavage activity and/or protein stability

Spear ED. et al, (2018), Disease Models & Mechanisms, 11

PIP2 Binding Site on a Human TRP Channel: Simulation Studies of PKD2

Wang Q. et al, (2018), BIOPHYSICAL JOURNAL, 114, 397A - 397A

The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery

Bradley AR. et al, (2017), Essays in Biochemistry, 61, 495 - 503

symmetric mechanosensitivity in a eukaryotic ion channel

Clausen MV. et al, (2017), Proceedings of the National Academy of Sciences, 114

Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel

Aryal P. et al, (2017), Structure, 25, 708 - 718.e2

Molecular insights into lipid-assisted Ca2+ regulation of the TRP channel Polycystin-2

Wilkes M. et al, (2017), Nature Structural & Molecular Biology, 24, 123 - 130

Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2)

Grieben M. et al, (2017), Nature Structural & Molecular Biology, 24, 114 - 122

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