Search results (201)
« Back to PublicationsInhibition of MLLT1 limits growth of KMT2A::AFF1 leukaemias without killing healthy haematopoietic stem cells
Journal article
Rajhansa S. et al, (2026), Experimental Hematology, 105458 - 105458
KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lysine on histone H3K9
Journal article
Belle R. et al, (2026), Nature Chemistry, 18, 823 - 834
Pleural fluid neutrophil extracellular traps are associated with disease severity and risk of one-year mortality in pleural infection. An observational, international, multicohort study (TORPIDS-3)
Journal article
Chu JY. et al, (2026), European Respiratory Journal, 2600113 - 2600113
The Heterocycle Isostere Explorer: A Computational Tool for the Discovery of Novel Aromatic Heterocyclic Isosteres
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Holland MTO. et al, (2026), Journal of Medicinal Chemistry, 69, 4408 - 4423
Assessing Aβ-independent effects of Module 42 on immune function in vitro.
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Ajith I. et al, (2026), Alzheimer's & dementia : the journal of the Alzheimer's Association, 22
A BRET biosensor for measuring uncompetitive engagement of PRMT5 complexes in cells
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Rothweiler EM. et al, (2025), Nature Communications, 16
Antifungal, antibacterial, and anti-inflammatory activity of glycerol dithionomonolaurate, an analog of glycerol monolaurate.
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Schlievert PM. et al, (2025), mSphere, 10
Transfer Learning for Heterocycle Retrosynthesis
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Wieczorek E. et al, (2025), Journal of Chemical Information and Modeling, 65, 7851 - 7861
MR1-ligand cross-linking identifies vitamin B6 metabolites as TCR-reactive antigens.
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Schmidlin T. et al, (2025), Cell reports methods, 5
A patent review of peptidylarginine deiminase 4 (PAD4) inhibitors (2014–present)
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Aiken SG. et al, (2025), Expert Opinion on Therapeutic Patents, 35, 611 - 621
Inhibition of MLLT1 limits growth of MLL-AF4 leukaemias without killing healthy haematopoietic stem cells
Preprint
Rajhansa S. et al, (2025)
Drug repurposing in amyotrophic lateral sclerosis (ALS)
Journal article
Carroll E. et al, (2025), Expert Opinion on Drug Discovery, 20, 447 - 464
Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor
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O’Brien DP. et al, (2025), Journal of Proteome Research, 24, 479 - 490
The Chemical Probes Portal – 2024: update on this public resource to support best-practice selection and use of small molecules in biomedical research
Journal article
Sanfelice D. et al, (2025), Nucleic Acids Research, 53, D1663 - D1669
A Live Cell BRET Probe to Quantify PRMT5-MTA Uncompetitive Target Engagement
Preprint
Rothweiler E. et al, (2025)