Search results (194)
« Back to PublicationsThe Heterocycle Isostere Explorer: A Computational Tool for the Discovery of Novel Aromatic Heterocyclic Isosteres
Journal article
Holland MTO. et al, (2026), Journal of Medicinal Chemistry, 69, 4408 - 4423
ssessing Aβ-independent effects of Module 42 on immune function in vitro.
Journal article
Ajith I. et al, (2026), Alzheimer's & dementia : the journal of the Alzheimer's Association, 22
BRET biosensor for measuring uncompetitive engagement of PRMT5 complexes in cells
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Rothweiler EM. et al, (2025), Nature Communications, 16
ntifungal, antibacterial, and anti-inflammatory activity of glycerol dithionomonolaurate, an analog of glycerol monolaurate.
Journal article
Schlievert PM. et al, (2025), mSphere, 10
Transfer Learning for Heterocycle Retrosynthesis
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Wieczorek E. et al, (2025), Journal of Chemical Information and Modeling, 65, 7851 - 7861
MR1-ligand cross-linking identifies vitamin B6 metabolites as TCR-reactive antigens.
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Schmidlin T. et al, (2025), Cell reports methods, 5
patent review of peptidylarginine deiminase 4 (PAD4) inhibitors (2014–present)
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Aiken SG. et al, (2025), Expert Opinion on Therapeutic Patents, 35, 611 - 621
Inhibition of MLLT1 limits growth of MLL-AF4 leukaemias without killing healthy haematopoietic stem cells
Preprint
Rajhansa S. et al, (2025)
Drug repurposing in amyotrophic lateral sclerosis (ALS)
Journal article
Carroll E. et al, (2025), Expert Opinion on Drug Discovery, 20, 447 - 464
Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor
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O’Brien DP. et al, (2025), Journal of Proteome Research, 24, 479 - 490
The Chemical Probes Portal – 2024: update on this public resource to support best-practice selection and use of small molecules in biomedical research
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Sanfelice D. et al, (2025), Nucleic Acids Research, 53, D1663 - D1669
Luminescence-based complementation assay to assess target engagement and cell permeability of glycolate oxidase (HAO1) inhibitors.
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Mackinnon SR. et al, (2025), Biochimie, 228, 71 - 81
Identification and characterization of human KALRN mRNA and Kalirin protein isoforms.
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Mould AW. et al, (2024), Cerebral cortex (New York, N.Y. : 1991), 34
Covalent Inhibitors of S100A4 Block the Formation of a Pro-Metastasis Non-Muscle Myosin 2A Complex
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Giroud C. et al, (2024), Journal of Medicinal Chemistry, 67, 18943 - 18956
Targeting APC/C Ubiquitin E3-Ligase Activation with Pyrimidinethylcarbamate Apcin Analogues for the Treatment of Breast Cancer.
Journal article
Kapanidou M. et al, (2024), Biomolecules, 14