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Search results (25)

« Back to Publications

DNA methyltransferase inhibitors in oncology: clinical progress, limitations and future directions.

Michael DC. and Mehdipour P., (2026), Epigenomics, 1 - 29

comprehensive tRNA pseudouridine map uncovers targets dependent on human stand-alone pseudouridine synthases

Xu H. et al, (2025), Nature Cell Biology, 27, 2186 - 2197

Repeats mimic pathogen-associated patterns across a vast evolutionary landscape.

Šulc P. et al, (2025), Cell genomics, 5

Chronic Viral Mimicry Induction following p53 Loss Promotes Immune Evasion.

Ishak CA. et al, (2025), Cancer discovery, 15, 793 - 817

DAR1: from basic mechanisms to inhibitors.

Rehwinkel J. and Mehdipour P., (2025), Trends in cell biology, 35, 59 - 73

Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways.

Feng S. et al, (2024), Nature communications, 15

In vivo CRISPR screens identify a dual function of MEN1 in regulating tumor-microenvironment interactions.

Su P. et al, (2024), Nature genetics, 56, 1890 - 1902

Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer.

Hosseini A. et al, (2024), Cell reports, 43

Ratio of stemness to interferon signalling as a biomarker and therapeutic target of myeloproliferative neoplasm progression to acute myeloid leukaemia

de Castro FA. et al, (2024), British Journal of Haematology, 204, 206 - 220

macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma.

Nikolic A. et al, (2023), Nature communications, 14

Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer

Hosseini A. et al, (2023)

PRMT inhibition induces a viral mimicry response in triple-negative breast cancer.

Wu Q. et al, (2022), Nature chemical biology, 18, 821 - 830

The next generation of DNMT inhibitors

Mehdipour P. et al, (2021), Nature Cancer, 2, 1000 - 1001

DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells

Loo Yau H. et al, (2021), Molecular Cell, 81, 1469 - 1483.e8

Publisher Correction: Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency.

Mehdipour P. et al, (2021), Nature, 591

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