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Search results (103)

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Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor

O’Brien DP. et al, (2024)

Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function

Carling PJ. et al, (2023), Autophagy, 19, 692 - 705

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

O’Brien DP. et al, (2022)

Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.

Szykowska A. et al, (2021), Structure (London, England : 1993), 29, 1241 - 1252.e5

Tackling gaps in developing life‐changing treatments for dementia

Mauricio R. et al, (2019), Alzheimer's & Dementia: Translational Research & Clinical Interventions, 5, 241 - 253

novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6

Priestley RS. et al, (2019), Journal of Pharmacological and Toxicological Methods, 95, 47 - 55

Development of a high-content imaging-based technique to measure Dickkopf-1 binding to low-density lipoprotein receptor-related protein 6

Priestley RS. et al, (2019), BRITISH JOURNAL OF PHARMACOLOGY, 176, 2990 - 2990

Small vessels, dementia and chronic diseases – molecular mechanisms and pathophysiology

Horsburgh K. et al, (2018), Clinical Science, 132, 851 - 868

standardized clinical evaluation of phenotypic diversity in diabetic polyneuropathy

Scholz J. et al, (2016), Pain, 157, 2297 - 2308

Full and partial peroxisome proliferation-activated receptor-gamma agonists, but not delta agonist, rescue of dopaminergic neurons in the 6-OHDA Parkinsonian model is associated with inhibition of microglial activation and MMP expression

Sadeghian M. et al, (2012), Journal of Neuroimmunology, 246, 69 - 77

Down-regulation of the ATP-binding Cassette Transporter 2 (Abca2) Reduces Amyloid-β Production by Altering Nicastrin Maturation and Intracellular Localization

Michaki V. et al, (2012), Journal of Biological Chemistry, 287, 1100 - 1111

Full and partial peroxisome proliferation-activated receptor-gamma agonists, but not delta agonist, rescue of dopaminergic neurons in the 6-OHDA Parkinsonian model is associated with inhibition of microglial activation and MMP expression

Sadeghian M. et al, (2012), Journal of Neuroimmunology

Neuroprotection by the selective iNOS inhibitor GW274150 in a model of Parkinson disease

Broom L. et al, (2011), Free Radical Biology and Medicine, 50, 633 - 640

Xenon reduces activation of transient receptor potential vanilloid type 1 (TRPV1) in rat dorsal root ganglion cells and in human TRPV1-expressing HEK293 cells

White JPM. et al, (2011), Life Sciences, 88, 141 - 149

Key Role for gp130 Expressed on Peripheral Sensory Nerves in Pathological Pain

Andratsch M. et al, (2009), The Journal of Neuroscience, 29, 13473 - 13483

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