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Publications

Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins

Elegheert J. et al, (2018), Nature Protocols, 13, 2991 - 3017

Heparan Sulfate Organizes Neuronal Synapses through Neurexin Partnerships

Zhang P. et al, (2018), Cell, 174, 1450 - 1464.e23

Glutamate receptor δ2 serum antibodies in pediatric opsoclonus myoclonus ataxia syndrome

Berridge G. et al, (2018), Neurology, 91, e714 - e723

nandb—number and brightness in R with a novel automatic detrending algorithm

Nolan R. et al, (2017), Bioinformatics, 33, 3508 - 3510

Structural basis for GABAA receptor potentiation by neurosteroids

Miller PS. et al, (2017), Nature Structural & Molecular Biology, 24, 986 - 992

A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis

Altemose N. et al, (2017), eLife, 6

A point mutation in the ion conduction pore of AMPA receptor GRIA3 causes dramatically perturbed sleep patterns as well as intellectual disability

Davies B. et al, (2017), Human Molecular Genetics, 26, 3869 - 3882

Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation

Farhy-Tselnicker I. et al, (2017), Neuron, 96, 428 - 445.e13

Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins

Elegheert J. et al, (2017), Neuron, 96, 242 - 244

Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins

Elegheert J. et al, (2017), Neuron, 95, 896 - 913.e10

A GluD Coming-Of-Age Story

Yuzaki M. and Aricescu AR., (2017), Trends in Neurosciences, 40, 138 - 150

Structural basis for integration of GluD receptors within synaptic organizer complexes

Elegheert J. et al, (2016), Science, 353, 295 - 299

Initiation of T cell signaling by CD45 segregation at 'close contacts'

Chang VT. et al, (2016), Nature Immunology, 17, 574 - 582

Transsynaptic Modulation of Kainate Receptor Functions by C1q-like Proteins

Matsuda K. et al, (2016), Neuron, 90, 752 - 767

A Computational Model for the AMPA Receptor Phosphorylation Master Switch Regulating Cerebellar Long-Term Depression

Gallimore AR. et al, (2016), PLOS Computational Biology, 12, e1004664 - e1004664

Characterizing the RPTP sigma Mediated Proteoglycan Switch As a Target for Rheumatoid Arthritis Therapy

Doody KM. et al, (2015), ARTHRITIS & RHEUMATOLOGY, 67

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

Taylor JC. et al, (2015), Nature Genetics, 47, 717 - 726

Targeting phosphatase-dependent proteoglycan switch for rheumatoid arthritis therapy

Doody KM. et al, (2015), Science Translational Medicine, 7, 288ra76 - 288ra76

Anterograde C1ql1 Signaling Is Required in Order to Determine and Maintain a Single-Winner Climbing Fiber in the Mouse Cerebellum

Kakegawa W. et al, (2015), Neuron, 85, 316 - 329

Extracellular regulation of type IIa receptor protein tyrosine phosphatases: mechanistic insights from structural analyses

Coles CH. et al, (2015), Seminars in Cell & Developmental Biology, 37, 98 - 107

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