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Ubiquitin ligases: guardians of mammalian development

Journal article

Cruz Walma DA. et al, (2022), Nature Reviews Molecular Cell Biology

Target 2035-update on the quest for a probe for every protein

Journal article

Mueller S. et al, (2021), RSC MEDICINAL CHEMISTRY

Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe.

Journal article

Röhm S. et al, (2021), Journal of medicinal chemistry, 64, 13451 - 13474

PRMT5 inhibition reduces viability and stemness of pediatric high grade glioma.

Conference paper

Brown EJ. et al, (2021), CANCER RESEARCH, 81

Challenges and Opportunities for Drug Repositioning in Fibrodysplasia Ossificans Progressiva

Journal article

Ventura F. et al, (2021), Biomedicines, 9, 213 - 213

ALK2 Receptor Kinase Association with FKBP12.6 Is Structurally Conserved with the ALK2-FKBP12 Complex

Journal article

Williams E. et al, (2021), Biomedicines, 9, 129 - 129

DFG-1 Residue Controls Inhibitor Binding Mode and Affinity, Providing a Basis for Rational Design of Kinase Inhibitor Selectivity

Journal article

Schröder M. et al, (2020), Journal of Medicinal Chemistry, 63, 10224 - 10234

Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma.

Journal article

Ensan D. et al, (2020), Journal of medicinal chemistry, 63, 4978 - 4996

A Highly Selective Chemical Probe for Activin Receptor-like Kinases ALK4 and ALK5

Journal article

Hanke T. et al, (2020), ACS Chemical Biology

Janus kinase inhibition for autoinflammation in patients with DNASE2 deficiency

Journal article

Hong Y. et al, (2020), Journal of Allergy and Clinical Immunology, 145, 701 - 705.e8

Targeted protein degradation: expanding the toolbox

Journal article

Schapira M. et al, (2019), Nature Reviews Drug Discovery

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