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DFG-1 Residue Controls Inhibitor Binding Mode and Affinity, Providing a Basis for Rational Design of Kinase Inhibitor Selectivity

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Schröder M. et al, (2020), Journal of Medicinal Chemistry, 63, 10224 - 10234

Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma.

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Ensan D. et al, (2020), Journal of medicinal chemistry, 63, 4978 - 4996

A Highly Selective Chemical Probe for Activin Receptor-like Kinases ALK4 and ALK5

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Hanke T. et al, (2020), ACS Chemical Biology

Janus kinase inhibition for autoinflammation in DNASE2 deficiency

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Hong Y. et al, (2019), Journal of Allergy and Clinical Immunology

Targeted protein degradation: expanding the toolbox

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Schapira M. et al, (2019), Nature Reviews Drug Discovery

Lessons from LIMK1 enzymology and their impact on inhibitor design

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Salah E. et al, (2019), Biochemical Journal

Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase

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Chen Z. et al, (2019), Structure, 27, 1395 - 1404.e4

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