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Publications

Characterization of meiotic recombination intermediates through gene knockouts in founder hybrid mice.

Davies B. et al, (2023), Genome research

Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2

Broadway-Stringer S. et al, (2023), Cells, 12, 721 - 721

Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression.

Mattis KK. et al, (2023), Diabetologia

Tissue-Specific Roles for the Slit-Robo Pathway During Heart, Caval Vein, and Diaphragm Development.

Zhao J. et al, (2022), J Am Heart Assoc

A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness.

Issler N. et al, (2022), J Am Soc Nephrol

Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages

Navarro-Guerrero E. et al, (2021), Scientific Reports, 11

Altering the Binding Properties of PRDM9 Partially Restores Fertility across the Species Boundary

Davies B. et al, (2021), Molecular Biology and Evolution

Precisely Tuned Inhibition of HIF Prolyl Hydroxylases Is Key for Cardioprotection After Ischemia

Jatho A. et al, (2021), Circulation Research, 128, 1208 - 1210

When the genome bluffs: a tandem duplication event during generation of a novel Agmo knockout mouse model fools routine genotyping.

Sailer S. et al, (2021), Cell Biosci, 11

Phenotype of a transient neonatal diabetes point mutation (SUR1-R1183W) in mice

Sachse G. et al, (2021), Wellcome Open Research, 5, 15 - 15

Replacement of surgical vasectomy through the use of wild-type sterile hybrids

Preece C. et al, (2021), Lab Animal

The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour.

Castroflorio E. et al, (2020), Cellular and molecular life sciences : CMLS

Fluorescent PSC-Derived Cardiomyocyte Reporter Lines: Generation Approaches and Their Applications in Cardiovascular Medicine

Sontayananon N. et al, (2020), Biology, 9, 402 - 402

Electroporation and genetic supply of Cas9 increase the generation efficiency of CRISPR/Cas9 knock-in alleles in C57BL/6J mouse zygotes.

Alghadban S. et al, (2020), Scientific reports, 10

The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates

Hinch AG. et al, (2020), Molecular Cell, 79, 689 - 701.e10

Phenotype of a transient neonatal diabetes point mutation (SUR1-R1183W) in mice

Sachse G. et al, (2020), Wellcome Open Research, 5, 15 - 15

A high-resolution map of non-crossover events reveals impacts of genetic diversity on mammalian meiotic recombination

Li R. et al, (2019), Nature Communications, 10

A high-resolution map of non-crossover events reveals impacts of genetic diversity on mammalian meiotic recombination

Li R. et al, (2019), Nature Communications, 10

Loss of ZnT8 function protects against diabetes by enhanced insulin secretion.

Dwivedi OP. et al, (2019), Nat Genet

Systemic silencing of Phd2 causes reversible immune regulatory dysfunction

Yamamoto A. et al, (2019), Journal of Clinical Investigation, 129, 3640 - 3656

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